Of course, the main question of tourists traveling to South Africa is whether vaccinations are required in Durban. According to official sources, special vaccinations are not required for traveling to Durban. But you should realize that you are traveling to another country with a different climate, food and water.
Therefore, if possible, it is better to get vaccinations against hepatitis A and B before traveling to Durban. Also, often when asked what vaccinations are required in Durban, the recommendation to get vaccinated against malaria and yellow fever is often answered. There are traditionally a lot of mosquitoes in the country. But in principle, various repellents, which can be purchased locally, are a good way to save you from them.