There is a train running between Fiumicino Airport and Rome Termini railway station in Rome. The journey takes about 30 minutes. From the station in the capital of Italy, you can then transfer to a direct high-speed train to Grosseto. In turn, the city of Castiglione della Pescaia is located near the administrative center of Grosseto. Detailed train schedules can be found on the railway's website.
Buses traveling to Castiglione della Pescaia stop at the Grosseto station square. It is also possible to reach the resort town by taxi, but it is the most expensive option.
The most convenient means of transportation in Italy is by train or a rented car. When renting a car, it should be noted that when entering a toll road section, you need to take a ticket from the machine, which should then be presented to the toll booth attendant when exiting the toll road. For example, on the road from Rome to Castiglione della Pescaia, there are two toll booths with a total cost of about 4 EUR.